Estrogen is a vital hormone that helps support the reproductive organs. Its metabolism is linked to diet, lifestyle, and genetic makeup.
Just like our bodies, our surroundings too carry varying degrees of estrogen. Plastic containers, nail polish, receipts—our households feature more of the hormone than most people know. And while the body can absorb these environmental estrogens (also known as xenoestrogens) in the same way it can produce estrogen naturally, it’s important to maintain a sense of balance.
This is because estrogen dominance—that is, the dominance of estrogen over progesterone—can lead to undesired health effects.1,2
This is where an environmental estrogen detox may serve you. There are a number of steps you can take to help reduce the amount of estrogen in your environment:
1. Use only skincare and household products with naturally derived ingredients.
o Take a look at the ingredients your favorite products contain. Many makeup, skincare, and even sunscreen brands rely on environmental estrogens like parabens and phthalates to achieve the results they promise. To stabilize your estrogen levels, search for alternatives that feature only naturally derived ingredients. The same applies to scented candles and air fresheners.
o It’s true as well for laundry and other cleaning products. Many fabric softeners and household cleaners, for instance, contain petrochemicals that may serve as environmental estrogens. To address this, search for organic household products whenever possible. Typically, products with fewer ingredients listed on the label are less likely to contain xenoestrogens.
2. Assess your furniture.
o Many home furnishings include xenoestrogens as well. Brominated flame-retardants (BFRs) are the most common and can be found in mattresses, carpets, electronics, and more.
o However, since the National Institute of Environmental Health Sciences determined that BFRs disrupt the endocrine system,3 you may want to shop for BFR-free furniture. Focus your search on ecofriendly companies that offer pieces made with only naturally derived ingredients. Steer clear of finishes and varnishes that contain chemicals, which may also act as environmental estrogens and potentially throw your hormonal balance out of whack.
3. Avoid storing food in plastic containers.
o While convenient, plastic containers—along with water bottles, bags, and other items made from plastic—include chemicals that mimic estrogen in the body.4 Two of these chemicals, bisphenol-A (BPA) and bisphenol-S (BPS), are especially detrimental in extreme temperatures. In particular, high heat can cause BPA and BPS to break down and leach into foods and liquids. Substitute plastic containers with glass or stainless steel to keep environmental estrogens at bay.
o In addition, you may want to avoid canned goods, as cans tend to feature plastic linings. The National Work Group for Safe Markets, in a 2010 study, determined that more than 90% of the cans it tested contained BPA.5 Receipt paper contains BPA as well, so say “no thank you” to unneeded receipts plus think about emptying your receipt drawer to further reduce the xenoestrogens in your household.
4. Use a water filter.
o The tap water in your area could be harboring environmental estrogens like fluoride, chlorine, and other chemicals. In a 2008 study across nine states, the U.S. Geological Survey found municipal water to contain 85 manmade chemicals.6
o That’s no small amount. Purchase a quality water filter to stay hydrated while keeping xenoestrogens at bay.
5. Eat organic produce, meat, and dairy products.
o Some farms feed their livestock drugs containing estrogen. This is meant to induce weight gain in the animals and increase the amount of meat these farms can sell. To avoid consuming meat and dairy products containing estrogenic drugs, choose grass-fed and organic options whenever possible.
o Similarly, make an effort to purchase organic produce, which contains lower levels of pesticides that act as environmental estrogens.7 And even if you do pick up organic produce, be sure to rinse your fruits and vegetables in filtered water as an extra precautionary measure.
6. Exercise on a regular basis and be sure to sweat
o The improved circulation of lymph and blood helps carry the chemicals to the liver to be detoxified. The toxic estrogens can be eliminated in the sweat. Try FIR saunas too.
o Physical activity is another effective way to counter the effects of estrogen dominance and complete an environmental estrogen detox. Research indicates that regular exercise reduces estrogen levels significantly.
o A 2011 study revealed that premenopausal women who performed five hours of aerobic exercise per week lowered their estrogen levels by 19%.8 In addition, a study conducted in 2013 revealed that aerobic exercise can help the body metabolize estrogen.9
These are just some of the steps you can take to help lower estrogen levels in your environment and body. Note that an estrogenic detox is best completed by making small, conscious changes.
Include these nutrients in your diet to support detoxifying the bad estrogen metabolites that can cause harmA significant body of literature has identified a number or nutrients, botanicals and nutrient compounds which have varying effects on the estrogen-metabolizing and detoxifying pathways. Implementation of many of these compounds through an individualized process affords great potential for those affected by the potentially deleterious effects of aberrant estrogen metabolism.
Let’s take a closer look at a handful of these nutraceuticals and botanicals.
· DIM (diindolylmethane) – DIM is a compound from cruciferous vegetables and is used to stimulate 2 hydroxylation (neutral estrogen pathway) via CYP1A1 and reduce expression of 16 hydroxylation (potential harmful estrogen pathway) through inhibiting CYP3a4. There is far more potential therapeutic action to DIM, however. DIM has shown to reduce DNA hypermethylation of CpG islands (hallmark feature of cancer activity), reduce intestinal inflammation, function to mildly inhibit aromatase, and enhance DNA repair mechanisms.
· Scientific research shows DIM (diindolylmethane), a phytonutrient found in cruciferous vegetables, increases the level of “good” estrogens while reducing the level of “bad” estrogens.
· Flax seeds – Flax seeds are a promoter of CYP1A1 and an inhibitor of CYP1B1. Thus, flax seeds are promoters of 2 hydroxylation (neutral estrogen), and inhibitors of 4 hydroxylation (potentially undesirable). Flax also has shown to inhibit CYP3a4 and reduce the excretion of 16OHE1, another potentially problematic estrogen (1, 2).
· Berries – Numerous types of berries (blackberries, raspberries, grapes, blueberries) are a rich source of polyphenolic compounds, including ellagic acid. Ellagic acid is a promoter of glutathione transferase (GSTM) as well as NQO1 (quinone reductase) (3). These 2 enzymes are important in the detoxification of 3,4 semi-quinones. Additionally, ellagic acid has been shown to increase DNA repair genes, as well as reduce DNA adducts that have been formed by carcinogens (4,5).
· Grapefruit & Citrus peel (modified citrus pectin)– Are sources of hesperidin. Hesperidin at high doses inhibits CYP1B1 and also CYP3a4. Grapefruit is notorious for inhibiting CYP3a4 (6, 7). Citrus peel contains a considerable amount of hesperidin, that is especially true of dried tangerine peel. An assortment of studies done on hesperidin have found an overall increase in blood flow and circulation, reduction in blood pressure, and reduction in symptoms of cell adhesion factors, which may disrupt cancer activities (8).
· Calcium D-glucarate – is a form of calcium that promotes phase 2 glucuronidation. This phase 2 reaction makes molecules more water soluble. Additionally, it is believed that calcium d-glucarate is a beta glucuronidase inhibitor, which acts to prevent the reabsorption of detoxified estrogens through 2nd pass metabolism.
· Glutathione promoters and/or cofactors: NAC, lipoic acid, selenium, B-2, B-6, zinc
Natural skin care products
1. Travis RC, Key TJ. Oestrogen exposure and breast cancer risk. Breast Cancer Research: BCR. 5.5. 2003:239-247.
2. Schulster M et al. The role of estradiol in male reproductive function. Asian J Androl. 2016;18(3):435–440.
3. Birnbaum LS et al. Brominated flame retardants: cause for concern? Environ Health Perspect. 2004;112(1):9–17.
4. Yang CZ et al. Most plastic products release estrogenic chemicals: a potential health problem that can be solved. Environ Health Perspect. 2011;119(7):989–996.
5. No silver lining: an investigation into bisphenol A in canned foods. National Work Group for Safe Markets. http://www.ej4all.org/contaminatedwithoutconsent/downloads/NoSilverLining-Report.pdf. Published May 2010. Accessed March 29, 2018.
6. Martins C. Sample concentration and analysis of human hormones in drinking water. Thermo Fisher Scientific. http://nemc.us/docs/2015/presentations/Mon-High%20Performance%20Liquid%20Chromatography%20in%20Environmental%20Monitoring-16.8-Martins.pdf. Published 2015. Accessed March 29, 2018.
7. Nicolopoulou-Stamati P et al. Chemical pesticides and human health: the urgent need for a new concept in agriculture. Front Public Health. 2016;4:148.
8. Kossman DA et al. Exercise lowers estrogen and progesterone levels in premenopausal women at high risk of breast cancer. J Appl Physiol (1985). 2011;111(6):1687–1693.
9. Smith AJ et al. The effects of aerobic exercise on estrogen metabolism in healthy premenopausal women. Cancer, Epidemiology, Biomarkers & Prevention. 22.5. 2013:756–764.
PectaSol-C Modified Citrus Pectin
$39.95 - $82.95
PectaSol-C® is the most advanced and effective Modified Citrus Pectin (MCP) supplement available. Proven to be a safe, gentle and highly effective formula, extensive clinical and scientific research has shown that PectaSol-C® MCP can:
-Support Cellular Health*
-Support Healthy Immune Response*
-Support Healthy Detoxification*
What is PectaSol-C Modified Citrus Pectin?
This natural product is derived from the pith of citrus fruit peels, including lemons, limes, oranges and grapefruits, and is modified using a proprietary enzymatic and pH process. This unique modification process guarantees that PectaSol-C® MCP has the correct molecular weight necessary to promote optimal cellular health of the breasts, prostate, lungs and more.*
Supports Healthy Cells & Blocks Galectin-3*
Ongoing scientific research demonstrates PectaSol-C®s natural ability to support healthy cell growth and behavior by binding Galectin-3. MCP is a natural ligand for Galectin-3, a molecule present in large numbers on the surface of unhealthy cells.*
Removes Toxic Heavy Metals*
Published in 2006, a clinical trial demonstrated PectaSol-C® MCPs ability to bind and remove toxic heavy metals from the body, without affecting essential minerals. Heavy metal removal with PectaSol-C® MCP has been shown in multiple case studies to play a role in ongoing health maintenance. A hospital study in 2008 reported that PectaSol-C® significantly decreased toxic lead levels.*
Unique Modification Process
The pectin found in many fruits cannot be absorbed into the bloodstream due to its large molecular size. Only PectaSol-C® MCP is produced using a proprietary process that carefully controls the weight and structure of the pectin molecules. The result is Modified Citrus Pectin with a specific low molecular weight range less than 15 kilodaltons and a low degree of esterification. This means that it is readily and effectively absorbed into the bloodstream, where it can actively promote cellular health.*
Servings Per Container: 45
As a dietary supplement, for maximum support, take 6 capsules three times daily on an empty stomach, or as recommended by your health care practitioner.
For long term maintenance, take 6 capsules once daily on an empty stomach, or as recommended by your health care practitioner.
Serving Size: 6 capsules
Amount Per Serving
Total Carbohydrates ... 4 g
Dietary Fiber ... 3 g
Sodium ... 170 mg
Potassium ... 410 mg
PectaSol-C® Modified Citrus Pectin ... 4.8 g
Other Ingredients: Vegetable capsule (natural vegetable cellulose, water), stearic acid, magnesium stearate, silicon dioxide, microcrystalline cellulose.
Store in a cool, dry place with cap tightly closed.
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.